PE-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag (Site-specific conjugation)

PE-Labeled Human IL-1 RAcP / IL-1 R3, His Tag (ILP-HP2H3) is produced via site-specific conjugation of PE to Human IL-1 RAcP / IL-1 R3 Protein, His Tag under optimal conditions with a proprietary technology. PE-Labeled Human IL-1 RAcP, His Tag (ILP-HP2H3) is expressed from human 293 cells (HEK293) . It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3-1) .

Product Specifications

Background

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.7 kDa.

Accession Number

Q9NPH3-1

Expression Region

Ser 21 - Glu 359

Host

HEK293

Target

IL-1 RAcP

Conjugation

PE Labeled

Tag

C-10xHis

Source

Human

Applications

Please note that this product is NOT compatible to streptavidin detection system.

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.