Carbonic anhydrase inhibitor 21
Product Specifications
UNSPSC Description
Carbonic anhydrase inhibitor 21 (Compound 5h) is a selective carbonic anhydrase (hCA IX) inhibitor, with a Ki of 15.1 nM, and is highly selective against other investigated isoform. Carbonic anhydrase inhibitor 21 can be used for anticancer research[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-21.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(NC(C2=CC(C(NC3=CC=C(C=C3)S(N)(=O)=O)P(OC(C)C)(OC(C)C)=O)=CC=C2)P(OC(C)C)(OC(C)C)=O)C=C1)(N)=O
Molecular Weight
774.82
References & Citations
[1]Sobati M, et al. Sulfonamide-incorporated bis(α-aminophosphonates) as promising carbonic anhydrase inhibitors: Design, synthesis, biological evaluation, and X-ray crystallographic studies. Arch Pharm (Weinheim). 2024 Mar 18:e2400038.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158078/Carbonic-anhydrase-inhibitor-21-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158078/
Clinical Information
No Development Reported
Curated Selection
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