Β-Ala-Lys (AMCA)

<strong>β-Ala-Lys(AMCA)</strong> <strong>Catalog number:</strong> MDP0296 <strong>CAS Number: </strong>115035-45-5 <strong>Sequence: </strong>β-Alanyl-Nε-(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-acetyl)-L-lysine <strong>Amount:</strong> 1 mg <strong>Molecular Weight:</strong> 432.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Alghamdi OA, King N, Jones GL, Moens PDJ. A new use of β-Ala-Lys (AMCA) as a transport reporter for PEPT1 and PEPT2 in renal brush border membrane vesicles from the outer cortex and outer medulla Biochim Biophys Acta Biomembr. 2018 May;1860(5):960-964. 2: Wang C, Sun Y, Zhao FQ, Liu J, Liu H. Functional Characterization of Peptide Transporters in Bovine Mammary Epithelial Cells J Agric Food Chem. 2019 Jan 9;67(1):213-219. 3: Zimmermann M, Kappert K, Stan AC. U373-MG cells express PepT2 and accumulate the fluorescently tagged dipeptide-derivative β-Ala-Lys-N(ε)-AMCA Neurosci Lett. 2010 Dec 17;486(3):174-8. 4: Kottra G, Spanier B, Verri T, Daniel H. Peptide transporter isoforms are discriminated by the fluorophore-conjugated dipeptides β-Ala- and d-Ala-Lys-N-7-amino-4-methylcoumarin-3-acetic acid Physiol Rep. 2013 Dec 8;1(7):e00165. 5: Oakley MT, Oheix E, Peacock AF, Johnston RL. Computational and experimental investigations into the conformations of cyclic tetra-α/β-peptides J Phys Chem B. 2013 Jul 11;117(27):8122-34. 6: Bauer K. Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain Neurochem Res. 2005 Oct;30(10):1339-45. 7: Gharabli H, Rafiq M, Iqbal A, Yan R, Aduri NG, Sharma N, Prabhala BK, Mirza O. Functional Characterization of the Putative POT from Clostridium perfringens Biology (Basel). 2023 Apr 26;12(5):651. 8: Jensen JM, Ernst H, Wang X, Hald H, Ditta AC, Ismat F, Rahman M, Mirza O. Functional investigation of conserved membrane-embedded glutamate residues in the proton-coupled peptide transporter YjdL Protein Pept Lett. 2012 Mar;19(3):282-7. 9: Zimmermann M, Stan AC. PepT2 transporter protein expression in human neoplastic glial cells and mediation of fluorescently tagged dipeptide derivative beta-Ala-Lys-Nepsilon-7-amino-4-methyl-coumarin-3-acetic acid accumulation J Neurosurg. 2010 May;112(5):1005-14. <a href="https://pubmed.ncbi.nlm.nih.gov/35601254">10: Wang C, Zhao F, Liu J, Liu H. The ubiquitin ligase Nedd4-2 mediates the regulation of PepT2 by mTORC1 in bovine mammary epithelial cells Anim Nutr. 2022 Feb 10;10:12-18. </a> <br><strong>Products Related to β-Ala-Lys(AMCA) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>