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L-Isoleucine

L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro[1].

Product Specifications

CAS Number

[73-32-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/L-Isoleucine.html

Purity

99.90

Solubility

10 mM in DMSO|H2O : 25 mg/mL (ultrasonic)

Smiles

N[C@@H]([C@@H](C)CC)C(O)=O

Molecular Formula

C6H13NO2

Molecular Weight

131.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Mao X, et al. l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats[J]. Front Immunol. 2022 Jan 11;12:817583.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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