Boc-AEVD-CHO
Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2].
Product Specifications
CAS Number
[220094-15-5]
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/boc-aevd-cho.html
Purity
98.34
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
C[C@H](NC(OC(C)(C)C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O
Molecular Formula
C22H36N4O10
Molecular Weight
516.54
References & Citations
[1]Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273 (49) :32608-13.|[2]Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22 (35) :5457-70.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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