Cesium chloride
Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3].
Product Specifications
CAS Number
[7647-17-8]
UNSPSC
12352200
Hazard Statement
H361, H402
Target
Potassium Channel
Type
Biochemical Assay Reagents
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cesium-chloride.html
Purity
99.93
Solubility
H2O : ≥ 100 mg/mL
Smiles
[Cs]Cl
Molecular Formula
ClCs
Molecular Weight
168.36
Precautions
H361, H402
References & Citations
[1]Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258.|[2]Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130 (1) :19-27.|[3]Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46 (12) :1437-1445.|[4]O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28 (8) :1059-1065.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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