YF438
YF438 is an HDAC inhibitor with effective anticancer activity both in vitro and in vivo. YF438 inhibits the growth and metastasis of triple-negative breast cancer (TNBC) cells by blocking the interaction between HDAC and MDM2, inducing the dissociation of MDM2-MDMX, and promoting the degradation of MDM2[1].
Product Specifications
CAS Number
[2247210-09-7]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yf438.html
Smiles
O=C(CCCCCC(NO)=O)N(CC1=NOC(C2=CC=CC=C2)=N1)C3=CC=C(OC)C=C3
Molecular Formula
C23H26N4O5
Molecular Weight
438.48
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164550/YF438-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164550/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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