CFT-1297
CFT-1297 is a BET PROTAC degrader that can degrade BRD4[1].
Product Specifications
CAS Number
2154353-03-2
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cft-1297.html
Smiles
CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)Cl)=NC25CC5)C=C(C=C3)C6=CN(N=C6)CCCCCCCN7CCC(CC7)C8=CC=CC9=C8CN(C9=O)C%10CCC(NC%10=O)=O
Molecular Formula
C47H50ClN9O3
Molecular Weight
824.41
References & Citations
[1]Kroupova A, et, al. Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders. Nat Commun. 2024 Oct 15;15 (1) :8885.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![NF-kappaB p65 Recombinant Rabbit Monoclonal Antibody [SZ10-04]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82b60/imageurl/et1603-12.webp)
ET1603-12 100 µL
NF-kappaB p65 Recombinant Rabbit Monoclonal Antibody [SZ10-04]
Sign In for Pricing
View Details 