CFT-1297
CFT-1297 is a BET PROTAC degrader that can degrade BRD4[1].
Product Specifications
CAS Number
2154353-03-2
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cft-1297.html
Smiles
CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)Cl)=NC25CC5)C=C(C=C3)C6=CN(N=C6)CCCCCCCN7CCC(CC7)C8=CC=CC9=C8CN(C9=O)C%10CCC(NC%10=O)=O
Molecular Formula
C47H50ClN9O3
Molecular Weight
824.41
References & Citations
[1]Kroupova A, et, al. Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders. Nat Commun. 2024 Oct 15;15 (1) :8885.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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