AcrAP1

AcrAP1 (AP1-Z1) is an antimicrobial peptide found in the venom of the Arabian scorpion (Androctonus crassicauda) . AcrAP1 has antimicrobial activity and can inhibit the growth of Gram-positive and Gram-negative bacteria as well as yeast. AcrAP1 exerts antitumor activity by promoting apoptosis of cancer cells and inhibiting angiogenesis. AcrAP1 can be used in cancer therapy research[1].

Product Specifications

Product Name Alternative

AP1-Z1

UNSPSC

12352209

Target

Apoptosis; Bacterial; Fungal

Type

Peptides

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/acrap1.html

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=CC=C5)N

Molecular Formula

C97H150N22O21

Molecular Weight

1960.36

References & Citations

[1]Ma R, et al. In vitro and MD simulation study to explore physicochemical parameters for antibacterial peptide to become potent anticancer peptide[J]. Molecular Therapy-Oncolytics, 2020, 16: 7-19.