Monoclonal Glycoprotein D (HSV-2) Antibody, Mouse IgG1 (3H9) (MALS verified)

Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein D (gD) is a structural component of the herpes simplex virus type 1 (HSV-1) envelope which is essential for virus entry and fusion with host cells. gD plays an important role by binding to the host receptors such as herpes virus entry mediator (HVEM) and nectin-1, a member of the immunoglobulin (Ig) -like cell adhesion molecules.

Product Specifications

Background

CAS Number

9007-83-4

Host

Hybridoma

Origin Species

Mouse

Target

Glycoprotein D/gD (HSV)

Conjugation

Unconjugated

Tag

Mouse IgG1 | Mouse Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Purity

0.9

Bioactivity

Immobilized HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (MALS verified) (Cat. No. GLD-V52H4) at 2 μg/mL (100 μL/well) can bind Monoclonal Glycoprotein D (HSV-2) Antibody, Mouse IgG1 (3H9) (Cat. No. GLD-Y111) with a linear range of 0.195-6.25 ng/mL (QC tested).