Cyprodime
Cyprodime is a selective μ opioid receptor (MOR) antagonist with Kis of 5.4, 244.6, and 2187 nM for μ, δ, and κ, respectively[1].
Product Specifications
CAS Number
118111-54-9
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
CO[C@@]12[C@]3(CC(CC2)=O)C4=C(OC)C=CC=C4C[C@@]1([H])N(CC5CC5)CC3
Molecular Formula
C22H29NO3
Molecular Weight
355.47
References & Citations
[1]Márki A, et al. Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [35S]GTPgammaS binding assays. Eur J Pharmacol. 1999;383 (2) :209-214.|[2]Zhang Z, , et al. Role of µ, κ, and δ opioid receptors in tibial inhibition of bladder overactivity in cats. J Pharmacol Exp Ther. 2015;355 (2) :228-234.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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