Phospho-Jak1 (Tyr1034/1035) Rabbit PE Conjugate

<strong>Phospho-Jak1 (Tyr1034/1035) Rabbit PE Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018540_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Tyrosine-protein kinase JAK1, Janus kinase 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kikkawa K, Matsuda T, Fujimuro M, Sekine Y. The Atypical Dual Specificity Phosphatase DUSP15 Regulates Jak1-Mediated STAT3 Activation Biol Pharm Bull. 2024;47(9):1487-1493._x000D_ 2: Sk MF, Jonniya NA, Roy R, Kar P. Phosphorylation-Induced Conformational Dynamics and Inhibition of Janus Kinase 1 by Suppressors of Cytokine Signaling 1 J Phys Chem B. 2022 May 5;126(17):3224-3239._x000D_ 3: Yu L, Deng Y, Wang X, Santos C, Davis IJ, Earp HS, Liu P. Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma Nat Commun. 2024 Jun 21;15(1):5292._x000D_ 4: Beckman JD, DaSilva A, Aronovich E, Nguyen A, Nguyen J, Hargis G, Reynolds D, Vercellotti GM, Betts B, Wood DK. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte-endothelial proadhesive interactions J Thromb Haemost. 2023 May;21(5):1366-1380._x000D_ 5: Macrì F, Vigorito I, Castiglione S, Faggiano S, Casaburo M, Fanotti N, Piacentini L, Vigetti D, Vinci MC, Raucci A. High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification Biomolecules. 2023 Dec 24;14(1):29._x000D_ 6: Park B, Lim JW, Kim H. Lycopene treatment inhibits activation of Jak1/Stat3 and Wnt/β-catenin signaling and attenuates hyperproliferation in gastric epithelial cells Nutr Res. 2019 Oct;70:70-81._x000D_ 7: Cha B, Lim JW, Kim H. Jak1/Stat3 is an upstream signaling of NF-κB activation in Helicobacter pylori-induced IL-8 production in gastric epithelial AGS cells Yonsei Med J. 2015 May;56(3):862-6._x000D_ 8: Zhang X, Wang X, Wang A, Li Q, Zhou M, Li T. CLDN10 promotes a malignant phenotype of osteosarcoma cells via JAK1/Stat1 signaling J Cell Commun Signal. 2019 Sep;13(3):395-405._x000D_ 9: Avey AM, Devos F, Roberts AG, Essawy ESE, Baar K. Inhibiting JAK1, not NF-κB, reverses the effect of pro-inflammatory cytokines on engineered human ligament function Matrix Biol. 2024 Jan;125:100-112._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35346999">10: Hong JK, Kim DY, Shin JS, Ryu YS, Moon JH, Koh DI, Lee S, Lee J, Lee WJ, Lee EY, Jung SA, Kim SC, Yu HN, Kim MJ, Hong SW, Park SS, Jung J, Kim SM, Kim EH, Jeong HR, Gong JH, Kim J, Kim TW, Jin DH. CJ14939, a Novel JAK Inhibitor, Increases Oxaliplatin-induced Cell Death Through JAK/STAT Pathway in Colorectal Cancer Anticancer Res. 2022 Apr;42(4):1813-1819. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Jak1 (Tyr1034/1035) Rabbit PE Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>