4,4-Difluoropiperidine (hydrochloride)

4,4-Difluoropiperidine hydrochloride is an intermediate. 4,4-Difluoropiperidine hydrochloride derivatives have anticancer activity against leukemia and pancreatic cancer[1][2].

Product Specifications

CAS Number

[144230-52-4]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Drug Intermediate

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-4-difluoropiperidine-hydrochloride.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1(F)CCNCC1.Cl

Molecular Formula

C5H10ClF2N

Molecular Weight

157.59

Precautions

H302, H315, H319, H335

References & Citations

[1]Woods JR, et al. Fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, as (19) f NMR probes in deuterium-free environments. J Med Chem. 2011 Nov 24;54 (22) :7934-41.|[2]Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022 Feb 24;65 (4) :3404-3419.