JNJ-7184
JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with the pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents RSV replication and transcription by inhibiting initiation or early elongation[1].
Product Specifications
CAS Number
2347368-51-6
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/jnj-7184.html
Smiles
C[C@H]1N(C(C2=NC3=CC(C4=CC=C([C@@H]5[C@@H](C(O)=O)C5)C=C4F)=NN3C(C6CC6)=C2)=O)CCC7=CC=CC=C71
Molecular Formula
C30H27FN4O3
Molecular Weight
510.56
References & Citations
[1]Brecht Bonneux, et al. JNJ-7184, a respiratory syncytial virus inhibitor targeting the connector domain of the viral polymerase. Antiviral Res. 2024 Jul:227:105907.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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