PLK4-IN-1
PLK4-IN-1 (Example A6) is a PLK4 inhibitor, with an IC50 of ≤ 0.1 μM[1].
Product Specifications
CAS Number
[1247001-12-2]
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plk4-in-1.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 260 mg/mL (ultrasonic)
Smiles
O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5
Molecular Formula
C18H14IN3O2
Molecular Weight
431.23
References & Citations
[1]Peter Brent Sampson, et al. KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME. Patent. WO2011123946A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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