Isovalerylcarnitine (chloride)

Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[1].

Product Specifications

CAS Number

[139144-12-0]

UNSPSC

12352211

Hazard Statement

H317, H319

Target

Endogenous Metabolite; Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/isovalerylcarnitine-chloride.html

Purity

99.48

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(C)CC(O[C@H](CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

Molecular Formula

C12H24ClNO4

Molecular Weight

281.78

Precautions

H317, H319

References & Citations

[1]Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148 (3) :1189-95.