SARS-CoV-IN-1

SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 15.4 and 133.2 nM; and IC90s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities[1].

Product Specifications

CAS Number

[888958-25-6]

UNSPSC

12352005

Target

Parasite; SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-in-1.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 41.67 mg/mL (ultrasonic)

Smiles

ClC1=CC2=C(C=C1)C(NC[C-]34[Fe+2]56789%10%11([C-]%12C8=C9C%10=C%11%12)C3(CNCCO)=C5C6=C47)=CC=N2

Molecular Formula

C23H16ClFeN3O

Molecular Weight

441.69

References & Citations

[1]Biot C, et al. Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities. J Med Chem. 2006 May 4;49 (9) :2845-9.