Fiboflapon sodium
Fiboflapon sodium (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood[1].
Product Specifications
CAS Number
1196070-26-4
Product Name Alternative
GSK2190915 (sodium salt) ; AM-803 sodium
UNSPSC
12352005
Target
FLAP; Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/GSK2190915-sodium-salt.html
Concentration
10mM
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C(O[Na])=O)(C)CC1=C(SC(C)(C)C)C2=CC(OCC3=CC=C(C)C=N3)=CC=C2N1CC4=CC=C(C5=CN=C(OCC)C=C5)C=C4
Molecular Formula
C38H42N3NaO4S
Molecular Weight
659.81
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
LTB4
Citation 01
Universiteit Leiden. 2025.|Biochem Pharmacol. 2025 Oct 23:117451.
Available Sizes
Frequently Asked Questions
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