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WRN inhibitor 17

Product Specifications

UNSPSC Description

WRN inhibitor 17 (Compound 250) is an orally active Werner Syndrome ATP dependent helicase enzyme (WRN) inhibitor, in particular inhibit WRN helicase domain activity. WRN inhibitor 17 is promising for research of cancers[1].

Target Antigen

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wrn-inhibitor-17.html

Smiles

COC[C@H]1C[C@H]([C@@H]([C@H](C1)C2=CC=C(C=C2)N(S(=O)(C3=CC4=C(N(C(C)=N4)C)C=C3)=O)C)C(O)=O)C(NC5=C(C=C(C=C5)C(F)(F)F)F)=O

Molecular Weight

690.70

References & Citations

[1]DEMARTINO, Michael P., et al. CHEMICAL COMPOUNDS AND USES THEREOF. WO2024246863. 2024 December 05.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-169423/WRN-inhibitor-17-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-169423/

Clinical Information

No Development Reported

CAS Number

3064599-40-9

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