WRN inhibitor 17

WRN inhibitor 17 (Compound 250) is an orally active Werner Syndrome ATP dependent helicase enzyme (WRN) inhibitor, in particular inhibit WRN helicase domain activity. WRN inhibitor 17 is promising for research of cancers[1].

Product Specifications

CAS Number

[3064599-40-9]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wrn-inhibitor-17.html

Smiles

COC[C@H]1C[C@H]([C@@H]([C@H](C1)C2=CC=C(C=C2)N(S(=O)(C3=CC4=C(N(C(C)=N4)C)C=C3)=O)C)C(O)=O)C(NC5=C(C=C(C=C5)C(F)(F)F)F)=O

Molecular Formula

C33H34F4N4O6S

Molecular Weight

690.70

References & Citations

[1]DEMARTINO, Michael P., et al. CHEMICAL COMPOUNDS AND USES THEREOF. WO2024246863. 2024 December 05.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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