WRN inhibitor 17
WRN inhibitor 17 (Compound 250) is an orally active Werner Syndrome ATP dependent helicase enzyme (WRN) inhibitor, in particular inhibit WRN helicase domain activity. WRN inhibitor 17 is promising for research of cancers[1].
Product Specifications
CAS Number
[3064599-40-9]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-17.html
Smiles
COC[C@H]1C[C@H]([C@@H]([C@H](C1)C2=CC=C(C=C2)N(S(=O)(C3=CC4=C(N(C(C)=N4)C)C=C3)=O)C)C(O)=O)C(NC5=C(C=C(C=C5)C(F)(F)F)F)=O
Molecular Formula
C33H34F4N4O6S
Molecular Weight
690.70
References & Citations
[1]DEMARTINO, Michael P., et al. CHEMICAL COMPOUNDS AND USES THEREOF. WO2024246863. 2024 December 05.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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