P2Y14R antagonist 2
P2Y14R antagonist 2 (compound 39) is a potent, selective and orally active P2Y14R antagonist with an IC50 value of 0.40 nM. P2Y14R antagonist 2 shows anti-inflammatory activity. P2Y14R antagonist 2 has the potential for the research of colitis[1].
Product Specifications
CAS Number
2989271-65-8
UNSPSC
12352211
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p2y14r-antagonist-2.html
Purity
99.56
Smiles
O=C(C1=CC(NC(C2=CC=C(C=C2)C)=O)=C(S1)OC3=NC=C(C=C3)F)O
Molecular Formula
C18H13FN2O4S
Molecular Weight
372.37
References & Citations
[1]Wang YH, et al. Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y14 Receptor Antagonists for Inflammatory Bowel Disease Treatment. J Med Chem. 2024 Jul 3.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y14 Receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470043-100 1x 100 µL
P21 / WAF1 (WA-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682038-500 1x 500 µL
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2038), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041067-100 1x 100 µL
HLA-DRB (HLA-DRB/1067), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details