LK-60
Product Specifications
UNSPSC Description
LK-60 is a potent DprE1 inhibitor. LK-60 effectively inhibits the proliferation of Mycobacterium tuberculosis. LK-60 has good safety profiles to gut microbiota and human cells[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lk-60.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N=C(N2C(NC3=CC=CC(C(F)(F)F)=C3)=CC(C)=N2)NC(CC)=C1
Molecular Weight
363.34
References & Citations
[1]Yang L, et al. Discovery of N-(1-(6-Oxo-1,6-dihydropyrimidine)-pyrazole) Acetamide Derivatives as Novel Noncovalent DprE1 Inhibitors against Mycobacterium tuberculosis. J Med Chem. 2024 Jan 17.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161178/LK-60-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161178/LK-60-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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