Carbazochrome

Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent[1].

Product Specifications

CAS Number

[69-81-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/carbazochrome.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic; adjust pH to 12 with NaOH)

Smiles

O=C1/C(C=C2C(O)CN(C)C2=C1)=N\NC(N)=O

Molecular Formula

C10H12N4O3

Molecular Weight

236.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Toshiaki Sendo, et al. Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2003 Sep;368 (3) :175-80.|[2]Toshiaki Sendo, et al. Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. Eur J Pharmacol. 2002 Aug 23;450 (2) :203-8.