18-Carboxy dinor Leukotriene B4

18-Carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4. In the liver, LTB4 is rapidly metabolized to 20-carboxy LTB4, which then undergoes β-oxidation to 18-carboxy dinor LTB4.

Product Specifications

CAS Number

[102674-12-4]

Product Name Alternative

18-Carboxy dinor LTB4

UNSPSC

12352211

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/18-carboxy-dinor-leukotriene-b4.html

Smiles

O=C(O)CC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O

Molecular Formula

C18H26O6

Molecular Weight

338.40

References & Citations

[1]Shirley, et al. Metabolism of leukotriene B4 in isolated rat hepatocytes. Involvement of 2,4-dienoyl-coenzyme a reductase in leukotriene B4 metabolism. J. Biol. Chem. 265, 16288-16295 (1990) .