[D-Arg1, D-Trp7,9, Leu11]-Substance P [Spantide]

<strong>[D-Arg1,D-Trp7,9,Leu11]-Substance P [Spantide]</strong> <strong>Catalog number:</strong> MDP0558 <strong>CAS Number: </strong>171358-00-2 <strong>Sequence: </strong>D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 1497.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Wiesenfeld-Hallin Z, Duranti R. D-Arg1, D-Trp7,9, Leu11-substance P (spantide) does not antagonize substance P-induced hyperexcitability of the nociceptive flexion withdrawal reflex in the rat Acta Physiol Scand. 1987 Jan;129(1):55-9. 2: Freedman J, Post C, Kåhrström J, Ohlen A, Mollenholt P, Owman C, Alari L, Hökfelt T. Vasoconstrictor effects in spinal cord of the substance P antagonist [D-Arg, D-Trp7,9 Leu11]-substance P (Spantide) and somatostatin and interaction with thyrotropin releasing hormone Neuroscience. 1988 Oct;27(1):267-78. 3: Fujino M, Kurosawa M, Saito H, Sato A, Swenson RS. Effects of a substance P analogue with antagonist properties ([D-Arg1, D-Trp7,9, Leu11]substance P) on spontaneous activity of the adrenal sympathetic nerve and its evoked reflex discharges in response to somatic afferent stimulation Neurosci Lett. 1987 Oct 5;80(3):315-20. 4: Bobyock E, Barbieri EJ, Chernick WS. Effects of substance P and substance P antagonists on rat salivary secretion J Dent Res. 1986 Dec;65(12):1427-31. 5: Eide PK. Effects of intrathecal substance P and a substance P antagonist on a reflex to noxious heat are independent of changes in tail skin temperature Acta Physiol Scand. 1990 Dec;140(4):539-43. 6: Jacoby HI, Lopez I, Wright D, Vaught JL. Differentiation of multiple neurokinin receptors in the guinea pig ileum Life Sci. 1986 Nov 24;39(21):1995-2003. 7: Wagner LE, Tomczuk BE, Yanni JM. Measurement of tachykinin-induced salivation in conscious rats J Pharmacol Methods. 1991 Aug;26(1):67-72. 8: Evans PD, Reale V, Merzon RM, Villegas J. Substance P modulation of the membrane potential of the Schwann cell of the squid giant nerve fibre Glia. 1990;3(5):393-404. 9: Tanabe T, Otani H, Bao L, Mikami Y, Yasukura T, Ninomiya T, Ogawa R, Inagaki C. Intracellular signaling pathway of substance P-induced superoxide production in human neutrophils Eur J Pharmacol. 1996 Mar 28;299(1-3):187-95. <a href="https://pubmed.ncbi.nlm.nih.gov/9154760">10: Akasu T, Yamada K. Neurokinin-1 (NK1) receptors mediate tachykinin-induced depression of GABA current in bullfrog sensory neurons Kurume Med J. 1997;44(1):33-41. </a> <br><strong>Products Related to [D-Arg1,D-Trp7,9,Leu11]-Substance P [Spantide] can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>