IRF3 Antibody [AMM02526G]
Product Specifications
Background
Tissue Location: Expressed constitutively in a variety of tissues.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF3 Antibody [AMM02526G].
Synonyms
Interferon regulatory factor 3, IRF-3, IRF3
Gene Name
IRF3 {ECO:0000303|PubMed:9803267, ECO:0000312|HGNC:HGNC:6118}
Gene ID
3661
UniProt
Q14653
Chromosomal Location
Cytoplasm. Nucleus Mitochondrion. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757) . When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757) . Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812) .
Applications
WB, IHC-P, FC, IF
Dilution
IF--1:25 FC--1:25 IHC-P--1:100~500 WB--1:2000
Function
2239456225636800273029531184697716846591169795672004943132972995168465911697956720049431223945622563680027302953161540842730295333440148168465912560981233440148
Molecular Weight
47219
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3661
Uniprot URL
https://www.uniprot.org/uniprot/Q14653
Available Sizes
Frequently Asked Questions
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