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IRF3 Antibody [AMM02526G]

Product Specifications

Background

Tissue Location: Expressed constitutively in a variety of tissues.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF3 Antibody [AMM02526G].

Synonyms

Interferon regulatory factor 3, IRF-3, IRF3

Gene Name

IRF3 {ECO:0000303|PubMed:9803267, ECO:0000312|HGNC:HGNC:6118}

Gene ID

3661

UniProt

Q14653

Chromosomal Location

Cytoplasm. Nucleus Mitochondrion. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757) . When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757) . Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812) .

Applications

WB, IHC-P, FC, IF

Dilution

IF--1:25 FC--1:25 IHC-P--1:100~500 WB--1:2000

Function

2239456225636800273029531184697716846591169795672004943132972995168465911697956720049431223945622563680027302953161540842730295333440148168465912560981233440148

Molecular Weight

47219

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3661

Uniprot URL

https://www.uniprot.org/uniprot/Q14653

Available Sizes

Frequently Asked Questions

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