17-Phenoxy trinor prostaglandin F2α ethyl amide

17-Phenoxy trinor prostaglandin F2α ethyl amide (17-Phenoxy trinor PGF2α ethyl amide) is an analog of Bimatoprost (HY-12956) . 17-Phenoxy trinor prostaglandin F2α ethyl amide is an agonist for Prostaglandin F2α Receptor (FP receptor) . 17-Phenoxy trinor prostaglandin F2α ethyl amide is potent to reduce the intraocular pressure and attenuate the glaucoma[1][2].

Product Specifications

CAS Number

[1421369-12-1]

Product Name Alternative

17-Phenoxy trinor PGF2α ethyl amide

UNSPSC

12352005

Hazard Statement

H225-H319-H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/17-phenoxy-trinor-prostaglandin-f2α-ethyl-amide.html

Smiles

O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CCOC2=CC=CC=C2)O)C/C=C\CCCC(N(CC)[H])=O

Molecular Formula

C25H37NO5

Molecular Weight

431.56

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P405-P501

References & Citations

[1]Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38 (14) :2375-81. |[2]Woodward DF, et al., Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024) . J Pharmacol Exp Ther. 2003 May;305 (2) :772-85.