SPARC Antibody (C-term) Antibody (Ascites) [AMM02446G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPARC Antibody (C-term) Antibody (Ascites) [AMM02446G].

Synonyms

SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine, SPARC, ON

Gene Name

SPARC

Gene ID

6678

UniProt

P09486

Chromosomal Location

Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane

Applications

Dilution

WB--1:500~1000

Form

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Function

Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca (2+) with a low affinity and an EF-hand loop that binds a Ca (2+) ion with a high affinity.