LK 204-545
LK 204-545 is a potent and highly selective β1-adrenoceptor antagonist. LK 204-545 is promising for research of cardiovascular diseases[1][2].
Product Specifications
CAS Number
83068-69-3
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lk-204-545.html
Smiles
O=C(NCCNCC(COC1=CC=C(C=C1C#N)OCCOCC2CC2)O)NC3=CC=C(C=C3)O
Molecular Formula
C25H32N4O6
Molecular Weight
484.54
References & Citations
[1]Louis S N S, et al. LK 204-545, a highly selective β1-adrenoceptor antagonist at human β-adrenoceptors[J]. European journal of pharmacology, 1999, 367 (2-3) : 431-435.|[2]Mistry SN, et al. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem. 2013 May 23;56 (10) :3852-65.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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