GLS2 Antibody [AMM04798G]
Product Specifications
Background
Tissue Location: Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
Synonyms
Glutaminase liver isoform, mitochondrial, GLS, 3.5.1.2, L-glutaminase, L-glutamine amidohydrolase, GLS2, GA
Gene Name
GLS2
Gene ID
27165
UniProt
Q9UI32
Chromosomal Location
Mitochondrion.
Applications
WB, IHC-P
Dilution
IHC-P--1:100~500 WB--1:1000-1:2000
Function
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha- ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Molecular Weight
66323
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLS2 Antibody [AMM04798G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=27165
Uniprot URL
https://www.uniprot.org/uniprot/Q9UI32
Available Sizes
Curated Selection
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