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PACSIN2 Antibody [APR17732G]

Product Specifications

Background

Tissue Location: Widely expressed.

Synonyms

Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II, PACSIN2

Gene Name

PACSIN2

Gene ID

11252

UniProt

Q9UNF0

Chromosomal Location

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1

Applications

WB

Dilution

WB--1:2000

Function

Regulates the morphogenesis and endocytosis of caveolae (By similarity) . Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.

Molecular Weight

55739

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PACSIN2 Antibody [APR17732G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=11252

Uniprot URL

https://www.uniprot.org/uniprot/Q9UNF0

Available Sizes

Curated Selection

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