PACSIN2 Antibody [APR17732G]
Product Specifications
Background
Tissue Location: Widely expressed.
Synonyms
Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II, PACSIN2
Gene Name
PACSIN2
Gene ID
11252
UniProt
Q9UNF0
Chromosomal Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1
Applications
WB
Dilution
WB--1:2000
Function
Regulates the morphogenesis and endocytosis of caveolae (By similarity) . Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.
Molecular Weight
55739
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PACSIN2 Antibody [APR17732G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=11252
Uniprot URL
https://www.uniprot.org/uniprot/Q9UNF0
Available Sizes
Curated Selection
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