VCP Antibody [APR10678G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VCP Antibody [APR10678G].

Synonyms

Transitional endoplasmic reticulum ATPase, TER ATPase, 15S Mg (2+) -ATPase p97 subunit, Valosin-containing protein, VCP, VCP

Gene Name

VCP

Gene ID

7415

UniProt

P55072

Chromosomal Location

Cytoplasm, cytosol. Endoplasmic reticulum. Nucleus. Cytoplasm, Stress granule. Note=Present in the neuronal hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients (PubMed:15456787) . Present in the Lewy bodies specifically found in neurons from Parkinson disease patients (PubMed:15456787) . Recruited to the cytoplasmic surface of the endoplasmic reticulum via interaction with AMFR/gp78 (PubMed:16168377) Following DNA double-strand breaks, recruited to the sites of damage (PubMed:22120668) . Recruited to stalled replication forks via interaction with SPRTN (PubMed:23042605) . Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains (PubMed:27753622) Colocalizes with TIA1, ZFAND1 and G3BP1 in cytoplasmic stress granules (SGs) in response to arsenite-induced stress treatment (PubMed:29804830) .

Applications

WB, IF

Dilution

IF--0.059027777777778 WB--1:2000

Function

26565908298048302202044022120668230426072304260532152270161865102111899520104022277536222647172921822278218222782333555926692333

Molecular Weight

89322

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.