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SIRT1 Antibody [APR09944G]

Product Specifications

Background

Tissue Location: Widely expressed..

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SIRT1 Antibody [APR09944G].

Synonyms

NAD-dependent protein deacetylase sirtuin-1, hSIRT1, 351-, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1, SIRT1, SIR2L1

Gene Name

HGNC:14929

Gene ID

23411

UniProt

Q96EB6

Chromosomal Location

Nucleus, PML body. Cytoplasm. Nucleus. Note=Recruited to the nuclear bodies via its interaction with PML (PubMed:12006491) . Colocalized with APEX1 in the nucleus (PubMed:19934257) . May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (PubMed:15469825) Shuttles between nucleus and cytoplasm (By similarity) . Colocalizes in the nucleus with XBP1 isoform 2 (PubMed:20955178) {ECO:0000250|UniProtKB:Q923E4, ECO:0000269|PubMed:12006491, ECO:0000269|PubMed:15469825, ECO:0000269|PubMed:19934257, ECO:0000269|PubMed:20955178}

Applications

WB

Dilution

WB--1:1000

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

116725231200649114976264149802221512650615152190152054771546982515692560160791811616662816892051169988101728306617290224173342241750506117612497176200571793670718203716182966411866254618687677191884491922006219364925196901661993425720097625201008292020330420375098206209562067089320817729209551782114973021245319214712012150483221555002216981332170104721775285218071132184182221890893219472822227461624415752248247801546982515152190149802221497626415205477184858711848587121504832215048321918844915469825203750981546982518004385180043852150483218004385215048321167252312006491193649252180711314980222149762642184182215126506219472821515219017620057172830662010082920620956156925601689205112535671216981331616662817505061196901661793670720817729217010471729022420817729152054771733422416998810176124972067089321149730152054771733422420097625182037161993425718296641217752851868767720203304218908932155500222274616186625462095517830193097244157522482478031722219

Molecular Weight

81681

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=23411

Uniprot URL

https://www.uniprot.org/uniprot/Q96EB6

Available Sizes

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