SIRT1 Antibody [APR09944G]
Product Specifications
Background
Tissue Location: Widely expressed..
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SIRT1 Antibody [APR09944G].
Synonyms
NAD-dependent protein deacetylase sirtuin-1, hSIRT1, 351-, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1, SIRT1, SIR2L1
Gene Name
HGNC:14929
Gene ID
23411
UniProt
Q96EB6
Chromosomal Location
Nucleus, PML body. Cytoplasm. Nucleus. Note=Recruited to the nuclear bodies via its interaction with PML (PubMed:12006491) . Colocalized with APEX1 in the nucleus (PubMed:19934257) . May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (PubMed:15469825) Shuttles between nucleus and cytoplasm (By similarity) . Colocalizes in the nucleus with XBP1 isoform 2 (PubMed:20955178) {ECO:0000250|UniProtKB:Q923E4, ECO:0000269|PubMed:12006491, ECO:0000269|PubMed:15469825, ECO:0000269|PubMed:19934257, ECO:0000269|PubMed:20955178}
Applications
WB
Dilution
WB--1:1000
Form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
116725231200649114976264149802221512650615152190152054771546982515692560160791811616662816892051169988101728306617290224173342241750506117612497176200571793670718203716182966411866254618687677191884491922006219364925196901661993425720097625201008292020330420375098206209562067089320817729209551782114973021245319214712012150483221555002216981332170104721775285218071132184182221890893219472822227461624415752248247801546982515152190149802221497626415205477184858711848587121504832215048321918844915469825203750981546982518004385180043852150483218004385215048321167252312006491193649252180711314980222149762642184182215126506219472821515219017620057172830662010082920620956156925601689205112535671216981331616662817505061196901661793670720817729217010471729022420817729152054771733422416998810176124972067089321149730152054771733422420097625182037161993425718296641217752851868767720203304218908932155500222274616186625462095517830193097244157522482478031722219
Molecular Weight
81681
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23411
Uniprot URL
https://www.uniprot.org/uniprot/Q96EB6
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog