CYK18 Antibody (C-term) [APR15652G]
Product Specifications
Background
Tissue Location: Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Synonyms
Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
Gene Name
KRT18
Gene ID
3875
UniProt
P05783
Chromosomal Location
Cytoplasm, perinuclear region. Nucleus, nucleolus
Applications
WB
Dilution
WB--1:1000
Form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.
Molecular Weight
48058
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYK18 Antibody (C-term) [APR15652G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3875
Uniprot URL
https://www.uniprot.org/uniprot/P05783
Available Sizes
Curated Selection
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