JUPAntibody (Ascites) [APR16956G]
Product Specifications
Synonyms
Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
Gene Name
JUP
Gene ID
3728
UniProt
P14923
Chromosomal Location
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Cytoplasmic in a soluble and membrane-associated form
Applications
WB
Dilution
WB--1:100~1600
Form
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Function
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity) .
Molecular Weight
81745
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality JUPAntibody (Ascites) [APR16956G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3728
Uniprot URL
https://www.uniprot.org/uniprot/P14923
Available Sizes
Curated Selection
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