ITGAX/CD11c Antibody (N-term) [APR16921G]
Product Specifications
Background
Tissue Location: Predominantly expressed in monocytes and granulocytes
Synonyms
Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C
Gene Name
ITGAX
Gene ID
3687
UniProt
P20702
Chromosomal Location
Membrane; Single-pass type I membrane protein.
Applications
WB
Dilution
WB--1:500~1000
Form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Molecular Weight
127829
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGAX/CD11c Antibody (N-term) [APR16921G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3687
Uniprot URL
https://www.uniprot.org/uniprot/P20702
Available Sizes
Curated Selection
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