ITGAX/CD11c Antibody (N-term) [APR16921G]

Product Specifications

Background

Tissue Location: Predominantly expressed in monocytes and granulocytes

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGAX/CD11c Antibody (N-term) [APR16921G].

Synonyms

Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C

Gene Name

ITGAX

Gene ID

3687

UniProt

P20702

Chromosomal Location

Membrane; Single-pass type I membrane protein.

Applications

Dilution

WB--1:500~1000

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.