MAP3K11 Antibody (ascites) [APR17282G]

Product Specifications

Background

Tissue Location: Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K11 Antibody (ascites) [APR17282G].

Synonyms

HGNC:6850

Gene Name

HGNC:6850

Gene ID

4296

UniProt

Q16584

Chromosomal Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Location is cell cycle dependent

Applications

Dilution

WB--1:500~1000

Form

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Function

Activates the JUN N-terminal pathway. Required for serum- stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen- stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.