AZD 2066
AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease[1][2][3][5].
Product Specifications
CAS Number
934282-55-0
UNSPSC
12352005
Hazard Statement
H302, H361
Target
Calcium Channel; mGluR; Trk Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/azd-2066.html
Purity
99.8
Solubility
DMSO : 2 mg/mL (ultrasonic; warming)
Smiles
CN1C(C2=CC=NC=C2)=NN=C1O[C@@H](C3=NOC(C4=CC(Cl)=CC=C4)=C3)C
Molecular Formula
C19H16ClN5O2
Molecular Weight
381.82
Precautions
H302, H361
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MGluR5
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
