LIN28A Antibody [AMM06300G]
Product Specifications
Background
Tissue Location: Expressed in embryonic stem cells, placenta and testis. Tends to be up-regulated in HER2-overexpressing breast tumors
Synonyms
Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1
Gene Name
LIN28A
Gene ID
79727
UniProt
Q9H9Z2
Chromosomal Location
Cytoplasm. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:Q8K3Y3}. Cytoplasm, P-body. Cytoplasm, Stress granule. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8K3Y3}. Note=Predominantly cytoplasmic (PubMed:22118463) . In the cytoplasm, localizes to peri-endoplasmic reticulum regions and detected in the microsomal fraction derived from rough endoplasmic reticulum (RER) following subcellular fractionation May be bound to the cytosolic surface of RER on which ER-associated mRNAs are translated (By similarity) . Shuttle from the nucleus to the cytoplasm requires RNA-binding (PubMed:17617744) . Nucleolar localization is observed in 10-15% of the nuclei in differentiated myotubes (By similarity) . {ECO:0000250|UniProtKB:Q8K3Y3, ECO:0000269|PubMed:17617744, ECO:0000269|PubMed:22118463}
Applications
WB, IHC-P, IF
Dilution
WB--1:200~2000 IHC-P--1:100~500 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
2124787618951094197033962211846322898984
Molecular Weight
22743
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIN28A Antibody [AMM06300G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=79727
Uniprot URL
https://www.uniprot.org/uniprot/Q9H9Z2
Available Sizes
Curated Selection
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