2′-Deoxyadenosine 5′-monophosphate (disodium)

2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1].

Product Specifications

CAS Number

[2922-74-9]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-deoxyadenosine-5-monophosphate-disodium.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 15.38 mg/mL (ultrasonic)

Smiles

O[C@H]1C[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COP(O[Na])(O[Na])=O

Molecular Formula

C10H12N5Na2O6P

Molecular Weight

375.19

Precautions

H315, H319, H335

References & Citations

[1]Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14 (10) :e0223892.|[2]V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27 (2) :496-502.