What is the catalog number for CD31 (TFA)?

The catalog number for CD31 (TFA) is HY-P3444A.

What sizes are available for CD31 (TFA)?

CD31 (TFA) is available in the following size(s): 1 Each.

Is CD31 (TFA) in stock?

CD31 (TFA) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD31 (TFA)?

CD31 (TFA) is manufactured by QuantiMol.

What is the estimated delivery time for CD31 (TFA)?

Estimated delivery time for CD31 (TFA) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD31 (TFA)?

The safety data sheet for CD31 (TFA) is available here: http://file.medchemexpress.com/batch_PDF/HY-P3444A/.

CD31 (TFA)

CD31 (PECAM-1) TFA is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin (CPB) . CD31 TFA is also an ER-MP12 antigen, acts as a linker between mechanical stress, metabolism and inflammation. CD31 TFA peptide is able to sustain phosphorylation of the CD31 ITIM686 and of SHP2 and to inhibit TCR-induced T-cell activation[1]-[5].

Product Specifications

Product Name Alternative

PECAM-1 (TFA)

UNSPSC

12352209

Target

Bacterial; SHP2

Type

Peptides

Related Pathways

Anti-infection; Protein Tyrosine Kinase/RTK

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cd31-tfa.html

Solubility

10 mM in DMSO

Smiles

OC(C(F)(F)F)=O.O=C([C@H]1N(CCC1)C([C@H](C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](C(C)C)NC([C@H](CO)NC([C@H](CO)NC([C@H](C)NC([C@@H](NC([C@@H](N)CC(N)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC4=CNC5=CC=CC=C45

Molecular Formula

C121H203F3N36O31

Molecular Weight

2715.12

References & Citations

[1]Caligiuri G. Mechanotransduction, immunoregulation, and metabolic functions of CD31 in cardiovascular pathophysiology. Cardiovasc Res. 2019 Jul 1. 115 (9) :1425-1434.|[2]Ling V, et al. Structural identification of the hematopoietic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31) . Eur J Immunol. 1997 Feb. 27 (2) :509-14.|[3]Bruggisser J, et al. CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell Host Microbe. 2020 Jul 8. 28 (1) :69-78.e6.|[4]Caligiuri G. CD31 as a Therapeutic Target in Atherosclerosis. Circ Res. 2020 Apr 24. 126 (9) :1178-1189. |[5]Fornasa G, et al. TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. J Immunol. 2010 May 15. 184 (10) :5485-92.