WF-10129
WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway.
Product Specifications
CAS Number
[109075-64-1]
UNSPSC
12352005
Target
Akt; Apoptosis
Type
Natural Products
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/wf-10129.html
Smiles
OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](C)N[C@H](C(O)=O)CC(CC[C@@H](O)C)=O)=O
Molecular Formula
C20H28N2O8
Molecular Weight
424.44
References & Citations
[1]WF-10129, a novel angiotensin converting enzyme inhibitor produced by a fungus, Doratomyces putredinis
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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