Thiacloprid-d4
Thiacloprid-d4 is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].
Product Specifications
CAS Number
1793071-39-2
UNSPSC
12352005
Target
DNA Stain; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
N#C/N=C(SC([2H])([2H])C1([2H])[2H])/N1CC2=CN=C(Cl)C=C2
Molecular Formula
C10H5D4ClN4S
Molecular Weight
256.75
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Schuld, M., et al. Effects of Thiacloprid, a New Chloronicotinyl Insecticide, On the Egg Parasitoid Trichogramma cacaoeciae. Ecotoxicology 9, 197–205 (2000) .|[3]Verebová V, Želonková K, Holečková B, Staničová J. The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA. Physiol Res. 201968 (Suppl 4) :S459-S466.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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