TrkC Antibody [APR05995G]
Product Specifications
Background
Tissue Location: Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain
Synonyms
NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC
Gene Name
NTRK3
Gene ID
4916
UniProt
Q16288
Chromosomal Location
Membrane; Single-pass type I membrane protein.
Applications
WB, IHC-P
Dilution
IHC-P--1:100 WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Molecular Weight
94428
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TrkC Antibody [APR05995G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4916
Uniprot URL
https://www.uniprot.org/uniprot/Q16288
Available Sizes
Curated Selection
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