What is the catalog number for PFTK1 Antibody (N-term) [APR05931G]?

The catalog number for PFTK1 Antibody (N-term) [APR05931G] is APR05931G.

What sizes are available for PFTK1 Antibody (N-term) [APR05931G]?

PFTK1 Antibody (N-term) [APR05931G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does PFTK1 Antibody (N-term) [APR05931G] come in?

PFTK1 Antibody (N-term) [APR05931G] is available in 4 different pack sizes.

Is PFTK1 Antibody (N-term) [APR05931G] in stock?

PFTK1 Antibody (N-term) [APR05931G] is currently made to order / not held in immediate stock. Contact us for lead time.

PFTK1 Antibody (N-term) [APR05931G]

Product Specifications

Background

Tissue Location: Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PFTK1 Antibody (N-term) [APR05931G].

Synonyms

Cyclin-dependent kinase 14, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, hPFTAIRE1, CDK14, KIAA0834, PFTK1

Gene Name

CDK14

Gene ID

5218

UniProt

O94921

Chromosomal Location

Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note=Recruited to the cell membrane by CCNY

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.