IL1RN Antibody (C-term) [APR05755G]
Product Specifications
Background
Tissue Location: The intracellular form of IL1RN is predominantly expressed in epithelial cells
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL1RN Antibody (C-term) [APR05755G].
Synonyms
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
Gene Name
IL1RN
Gene ID
3557
UniProt
P18510
Chromosomal Location
[Isoform 1]: Secreted. [Isoform 3]: Cytoplasm.
Applications
FC, IF, WB
Dilution
WB--1:4000 WB--1:1000 FC--1:10~50 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Molecular Weight
20055
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3557
Uniprot URL
https://www.uniprot.org/uniprot/P18510
Available Sizes
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