ZNF281 Antibody (Center) [APR04782G]
Product Specifications
Synonyms
Zinc finger protein 281, GC-box-binding zinc finger protein 1, Transcription factor ZBP-99, Zinc finger DNA-binding protein 99, ZNF281, GZP1, ZBP99
Gene Name
ZNF281
Gene ID
23528
UniProt
Q9Y2X9
Chromosomal Location
Nucleus.
Applications
WB
Dilution
WB--1:1000
Function
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity) . Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.
Molecular Weight
96915
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZNF281 Antibody (Center) [APR04782G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23528
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2X9
Available Sizes
Curated Selection
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