Sqstm1 (S351) Antibody [APR04661G]

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Sqstm1 (S351) Antibody [APR04661G].

Cytoplasm, cytosol. Late endosome. Nucleus Endoplasmic reticulum. Lysosome. Cytoplasmic vesicle, autophagosome Nucleus, PML body {ECO:0000250|UniProtKB:Q13501}. Cytoplasm, myofibril, sarcomere. Note=In cardiac muscles, localizes to the sarcomeric band (By similarity) . May also localize to the hepatocellular carcinoma (By similarity) . Colocalizes with TRIM13 in the perinuclear endoplasmic reticulum (By similarity) . Commonly found in inclusion bodies containing polyubiquitinated protein aggregates (PubMed:20421418) . Co- localizes with TRIM5 in the cytoplasmic bodies (By similarity) . When nuclear export is blocked by treatment with leptomycin B, accumulates in PML bodies (By similarity) . {ECO:0000250|UniProtKB:Q13501, ECO:0000269|PubMed:20421418}

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.